ODCs

Click node...

2 OMIM references -
2 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

2 OMIM references -
1 associated gene
7 signs/symptoms

Parkinsonian-pyramidal syndrome

Early-onset generalized limb-onset dystonia

FBXO7	(UniProt - OMIM)		TOR1A	(UniProt - OMIM)
SNCA	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SNCA	(0.75)	TOR1A

Citations in the biomedical literature:

Parkinsonian-pyramidal syndrome		Early-onset generalized limb-onset dystonia
	Synonym(s): - Pallidopyramidal syndrome		Synonym(s): - DYT1 - Dystonia musculorum deformans - EOTD - Early-onset generalized torsion dystonia - Early-onset primary dystonia - Early-onset torsion dystonia - Idiopathic dystonia - Idiopathic torsion dystonia - Oppenheim dystonia

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Diseases of the nervous system -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: - Average age onset: adolescence / young Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: adolescence / young Average age of death: - Type of inheritance: autosomal dominant

	External references: 2 OMIM references - No MeSH references		External references: 2 OMIM references - No MeSH references

Early-onset generalized limb-onset dystonia
	Very frequent - Abnormal gait - Autosomal dominant inheritance - Autosomal recessive inheritance - Hypertonia / spasticity / rigidity / stiffness - Movement disorder - Muscle anomalies Frequent - Abnormal cry / voice / phonation disorder / nasal speech
Parkinsonian-pyramidal syndrome
(no data available)